
Cancer Treatment: Cancer is one of the most dangerous diseases. A team of scientists from the Institute of Advanced Study in Science and Technology (IASST), an institute of the Department of Science and Technology (DST), has developed new magnetic nanoparticles that will help promote cancer treatment.
Treatment will be done by increasing the temperature of tumor cells
The developed magnetic system using nanoparticles treats cancer by increasing the temperature of tumor cells. This system works through a method called magnetic hyperthermia to treat cancer. Cancer is considered one of the most dangerous diseases. Among the many available treatment methods, the most effective treatment for cancer cells is radiation therapy, chemotherapy, targeted therapy and stem cell transplantation.
Creating and controlling magnetic nanoparticles is challenging
All cancer treatment methods have demonstrated several side effects. Apart from being costly, the treatments are also difficult for many people. The IASST team focused on nanomagnets, which opened up a targeted heat generation process (hyperthermia) to treat cancer cells. This therapy comes with comparatively fewer side effects and is controlled by a magnetic field from outside. Due to the direct influence of various physical parameters of the nanomagnets on the self-heating efficacy, it is challenging to fabricate and control biocompatible coated magnetic nanoparticles with effective heat generation efficiency.
Thus, the team synthesized nanocrystalline cobalt chromite magnetic nanoparticles with different rare-earth Gd dopant contents using a conventional chemical co-precipitation route. The heterogeneous mixture of these magnetic nanoparticles in liquid form was used to heat under an applied alternating magnetic field."
The temperature of the cells is increased to 46 °C
"The heat generation method of magnetic nanoparticles can be used in treating cancer cells by raising the cell temperature to 46°C for a specific period of time, causing necrosis in the injured cells when applied to specific cancer locations," the researchers said. These findings were recently published in Nanoscale Advances, a peer-reviewed journal of the Royal Society of Chemistry, UK.
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