Will Alzheimer's no longer be incurable? Scientists challenge a long-standing belief.

News Topical, Digital Desk : Imagine a world where a serious disease like Alzheimer's could not only be prevented but also completely cured. It sounds like a miracle, considering medical science had given up on this disease for the past 100 years, considering it incurable. But now, American scientists have made a revolutionary discovery that has lit a new ray of hope. A new study claims that memory can be restored by correcting a specific balance in the brain.

What is this new discovery?

The study, published in the journal Cell Reports Medicine, has attracted worldwide attention. Researchers have found that Alzheimer's is primarily caused by an imbalance of a cellular energy molecule called NAD+.

In their research, scientists observed that the level of 'NAD Plus' drops rapidly in the brains of both humans suffering from Alzheimer's and mice modeling the disease.

Successful experiments were conducted on rats

To test this theory, scientists conducted laboratory studies on specially engineered mice that were genetically engineered to develop Alzheimer's symptoms, similar to humans. The mice included two types:

• One had a mutation in amyloid processing.
• Others had mutations in the tau protein.

When researchers restored the declining levels of NAD+ in the brains of these mice, the results were surprising.

The disease was cured even in the advanced stage

Dr. Andrew A. Piper and his team at the Harrington Discovery Institute at University Hospitals used a pharmacological agent called PC3-20 to restore the NAD+NAD balance in the brains of mice. The results were very encouraging:

• Disease prevention: Maintaining the NAD+ balance in mice that had not yet developed the disease prevented them from developing Alzheimer's.
• Recovery: Most notably, treatment of mice with advanced disease showed improved brain function.
• Memory restored: After treatment, both strains of mice completely regained their thinking ability.

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