Good protein is beneficial for the liver, it can also be helpful in preventing the risk of cancer:

News Topical, Digital Desk : There have been many changes in our eating habits in the last few decades. Dependence on processed food like pizza, burger, samosa, kachori, French fries has increased. Continuous consumption of such dishes leads to accumulation of more than five percent fat in the liver.

This fat causes inflammation, ballooning and further fibrosis in the liver cells. If liver fibrosis is not controlled, it turns into cirrhosis and later liver cancer. In a study conducted on 250 people in five groups from 2022 to 2024 at AIIMS, the result came that if the good protein (Procyanidinsin-1) of the cell is increased and the bad protein (Procyanidinsin-2) is controlled, then the number of T-regulatory (T-reg) cells of the immune system will improve.

Along with this, the protection of anti-oxidant genes will also be strengthened. This can stop or slow down the progression of the disease, making treatment possible before it reaches a dangerous stage like cirrhosis or liver cancer.

This study has been published in the Scientific Reports of Nature Journal on August 12. In the case of non-alcoholic fatty liver disease (NAFLD), when more than five percent fat accumulates, the liver cells start swelling. After this, the liver tissues start swelling, which is called ballooning.

When ballooning occurs in many tissues, bridging starts taking place. All the surrounding cells join with it and form clusters, which forms liver fibrosis. This condition is called non-alcoholic steatohepatitis (NASH). But when more fibrosis starts forming, it turns into cirrhosis. If it is not treated on time, it turns into liver cancer i.e. hepatocellular carcinoma. There is no medicine for it.

Bad proteins increase inflammation in the cell

AIIMS study found that there are two types of proteins in the cell - Prokineticin-1 (PK-1) and Prokineticin-2 (PK-2). Both have 40 percent similarity. In case of fatty liver, protein PK-1 decreased and PK-2 increased. PK-1 is a good protein because it keeps the immune system of the body balanced and helps in controlling inflammation. The immune system itself contains T-reg (T-regulatory) cells, whose number is also found to be reduced in people suffering from obesity. On the contrary, PK-2 is a bad protein, which increases inflammation of the cell in the disease. When the number of T-reg cells decreased, liver damage also increased.

Study done on patients in five groups

Five groups of obese NAFLD and non-obese NAFLD were formed in diabetes, metabolic syndrome, diabetes-metabolic syndrome as well as non-alcoholic fatty liver disease. The study was conducted under the leadership of Dr. Shyam Prakash, Additional Professor, Department of Laboratory Medicine, and was also supported by Dr. Shalimar of the Department of Gastroenterology, Dr. Naval Kishore Vikram of the Department of Medicine, as well as Dr. Medha and Dr. Shahid etc.