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News Topical, Digital Desk : You've often heard people say that certain foods become harder to digest as we age, but have you ever wondered why? Now, scientists have not only understood the root of this problem, but also discovered a brilliant way to help your intestines heal themselves.
Why do the intestines start becoming weak?
There is a very thin layer of cells inside our intestines, which is called 'Intestinal Epithelium'.
This lining is crucial for proper digestion and overall intestinal health. In a healthy human body, this lining completely renews itself every 3 to 5 days by shedding old cells.
However, as we age or when exposed to radiation during cancer treatment, this gut "renewal" process is disrupted. This process either slows significantly or stops completely. When this happens, inflammation in the intestines increases and digestive disorders like leaky gut syndrome develop.
Solution found in 'CAR T-cell therapy'
To address this problem, researchers used CAR T-cell therapy. This therapy directly targeted and eliminated old, senescent (damaged) cells that accumulate in the intestines over time.
Impressive results of testing on mice
This new technique was tested on mice, with very encouraging results:
- Intestinal regeneration: The mice's intestines began to regenerate and repair themselves faster.
- Reduced inflammation: Intestinal inflammation was significantly reduced.
- Improved digestion: The ability to absorb essential nutrients from food is greatly improved.
- Long-term protection: This treatment also protected the intestines from radiation damage. Most importantly, the benefits of this treatment lasted for a full year in the mice.
A new hope for the future
Initial tests on human intestinal cells also indicate that this approach is highly effective. This new scientific discovery could prove to be a boon for the elderly and cancer patients who struggle with digestive and intestinal weakness. It could significantly improve their intestinal health.
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