News Topical, Digital Desk : A Spanish research team claims to have developed a treatment that completely eliminates the most dangerous form of pancreatic cancer in lab mice. This cancer is considered one of the deadliest cancers in the world. This study was conducted at Spain's National Cancer Research Center (CNIO) under the leadership of scientist Mariano Barbacid. Let us tell you what claims have been made about it
What has come out in the research?
According to the research, scientists used a new combination of three drugs, which completely eliminated pancreatic tumors in mice. Most importantly, there were no signs of cancer returning after treatment. This six-year study also found that the treatment had very few side effects on the animals. Pancreatic cancer, especially pancreatic ductal adenocarcinoma, is considered deadly because it is highly resistant to treatment and is often detected late. Usually, single-drug treatments fail because cancer cells adapt quickly.
What does the researcher say?
This new therapy from CNIO takes a different approach. It combines not one, but three drugs to simultaneously shut down multiple life-saving processes in cancer. Researchers say this prevents cancer cells from adapting. Lab experiments showed that tumors in mice with advanced pancreatic cancer completely disappeared. Despite long-term monitoring, the tumors did not recur, which is considered extremely rare in this disease.
Waiting for the humans
The study was published in the prestigious journal Proceedings of the National Academy of Sciences (PNAS). Reviewers particularly highlighted the treatment's long-term efficacy and minimal side effects. Cancer experts say such results, without recurrence, are highly unusual in pancreatic cancer research. Following this discovery, excitement and skepticism were also seen on social media. Some hailed it as a major leap forward in treatment, while others questioned the straightforward labeling of it a "cure." Experts say that after the success in mice, human trials and a long process remain.
What is pancreatic cancer?
Pancreatic cancer is a disease that begins with abnormal cell growth in the pancreas. The pancreas is located behind the lower stomach and produces enzymes that aid digestion and hormones that regulate blood sugar. The most common type is pancreatic ductal adenocarcinoma.
This cancer often goes undetected in its early stages because symptoms often appear late. Symptoms include abdominal or back pain, weight loss, loss of appetite, jaundice, dark urine, fatigue, and a sudden increase in diabetes. If you experience these symptoms, consult a doctor immediately. In 80 to 85 percent of cases, symptoms appear late, and only 10 percent of patients survive for five years.
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